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Related Concept Videos

Acute Pharyngitis01:30

Acute Pharyngitis

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Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
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Diphtheria is an acute, toxin-mediated infectious disease that primarily affects the upper respiratory tract. It is caused by Corynebacterium diphtheriae, a Gram-positive, pleomorphic rod that lacks spore-forming capability and exhibits a characteristic club-shaped morphology under microscopic examination. While C. diphtheriae can asymptomatically colonize mucosal surfaces, clinical disease manifests only when the bacterial strain is lysogenized by a specific β-corynephage. This phage...
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Poliomyelitis01:17

Poliomyelitis

Poliomyelitis is caused by poliovirus, a small, non-enveloped, positive-sense RNA virus of the Picornaviridae family and Enterovirus genus. Transmission occurs primarily via the fecal-oral route, often through ingestion of contaminated water or food. The virus initially replicates in the oropharynx and intestinal mucosa, particularly in lymphoid tissues such as the tonsils, Peyer’s patches, and regional lymph nodes. Primary viremia follows, allowing dissemination throughout the body.In most...
Arboviral Encephalitis01:25

Arboviral Encephalitis

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Related Experiment Video

Updated: Jul 8, 2026

Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1
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Acute parotitis due to dengue virus.

J R Torres1, F Liprandi, A P Goncalvez

  • 1Instituto de Medicina Tropical, Universidad Central de Venezuela, Caracas, Venezuela. torresj@camelot.rect.ucv.ve.

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
|November 14, 2000
PubMed
Summary

Acute bilateral parotitis, or salivary gland swelling, can signal various health issues. This case highlights dengue fever as a rare cause, with dengue virus detected in saliva for the first time.

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Area of Science:

  • Infectious Diseases
  • Virology
  • Immunology

Background:

  • Acute bilateral parotitis is a recognized clinical manifestation across diverse conditions, including infections, autoimmune disorders, metabolic disturbances, and drug reactions.
  • The parotid glands, the largest salivary glands, can become inflamed and enlarged due to various systemic and local factors.

Observation:

  • A unique case of bilateral parotitis was observed in an immunocompetent individual diagnosed with dengue fever.
  • The patient presented with symmetrical swelling and inflammation of both parotid glands.

Findings:

  • This study provides the first documented evidence of dengue virus presence in the saliva of a patient with dengue fever-associated parotitis.
  • Laboratory confirmation of dengue virus infection was established.

Implications:

  • This finding expands the differential diagnosis for acute bilateral parotitis to include dengue fever, particularly in endemic regions.
  • The detection of dengue virus in saliva suggests potential salivary transmission routes, warranting further investigation.
  • Highlights the importance of considering viral etiologies in parotitis cases, even in immunocompetent patients.