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Cocaine-induced reflex sympathetic dystrophy.

D Gay1, A Singh

  • 1Department of Radiology, University of Missouri Health Sciences Center, Columbia, USA.

Clinical Nuclear Medicine
|November 18, 2000
PubMed
Summary
This summary is machine-generated.

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This case report details reflex sympathetic dystrophy (RSD) in a patient who self-administered cocaine intraarterially. Phentolamine treatment confirmed the diagnosis, highlighting a rare cause of RSD.

Area of Science:

  • Neurology
  • Pharmacology
  • Radiology

Background:

  • Reflex sympathetic dystrophy (RSD) is typically associated with trauma or neurological conditions.
  • Intraarterial drug administration can lead to severe complications.

Observation:

  • A patient with a history of intravenous drug abuse inadvertently injected cocaine into the femoral artery.
  • The patient presented with intense pain, swelling, and dermatologic changes.
  • Initial diagnostic workup, including radiographs and leukocyte studies, was inconclusive.

Findings:

  • Scintigraphic studies, specifically an abnormal bone scan, suggested RSD.
  • RSD was attributed to ischemic autonomic injury caused by cocaine's vasoconstrictor effects.
  • Diagnosis was supported by clinical improvement following phentolamine administration.

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Implications:

  • This case highlights a rare etiology of RSD following intraarterial cocaine administration.
  • It underscores the importance of considering unusual causes in complex pain syndromes.
  • Phentolamine may be an effective treatment for cocaine-induced RSD.