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Related Experiment Videos

Lichen scrofulosorum.

A Torrelo1, E Valverde, I G Mediero

  • 1Department of Dermatology, Hospital del Niño Jesús, Madrid, Spain.

Pediatric Dermatology
|November 21, 2000
PubMed
Summary
This summary is machine-generated.

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A papular eruption in a 12-month-old boy was diagnosed as lichen scrofulosorum, a rare manifestation of tuberculosis. Despite negative tests for Mycobacterium tuberculosis in the skin, the condition highlights a form of tuberculid requiring attention.

Area of Science:

  • Dermatology
  • Infectious Diseases
  • Pathology

Background:

  • Tuberculosis (TB) can present with various cutaneous manifestations.
  • Tuberculids are inflammatory skin reactions to Mycobacterium tuberculosis, often occurring when bacilli are not readily found in the skin.
  • Lichen scrofulosorum is a rare form of tuberculid.

Observation:

  • A 12-month-old boy with pulmonary tuberculosis developed a papular lichenoid eruption.
  • Histopathology of the skin biopsy revealed epithelioid granulomas.
  • Microbiological stains, cultures, and PCR for Mycobacterium tuberculosis in the skin biopsy were negative.

Findings:

  • The clinical and histological findings were consistent with lichen scrofulosorum.
  • This case represents a manifestation of Mycobacterium tuberculosis infection where direct evidence of the bacillus in the skin was not detected.

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  • Lichen scrofulosorum remains a diagnostic challenge in the context of TB.

    • Implications:

    • Lichen scrofulosorum, though rare, should be considered in the differential diagnosis of papular eruptions in patients with tuberculosis.
    • The case underscores the possibility of tuberculid reactions even in the absence of detectable mycobacteria in skin lesions.
    • Further research may elucidate the pathogenesis of tuberculids like lichen scrofulosorum.