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Infantile Transient Smooth Muscle Contraction of the Skin in Two Sisters
Sofía Granillo Fernández1, Agostina Alonzo Caldarelli1, Gisele Luty2
1Department of Dermatology, Hospital Dr. Ricardo Gutiérrez, La Plata, Argentina.
Pediatric Dermatology
|June 24, 2026
Summary
Infantile transient smooth muscle contraction of the skin (ITSMCS) is a rare newborn condition causing rippling skin. This report details two sisters diagnosed with this unusual smooth muscle disorder.
Area of Science:
- Pediatrics
- Dermatology
- Genetics
Background:
- Infantile transient smooth muscle contraction of the skin (ITSMCS) is a rare condition.
- It typically affects newborns' lower extremities.
- Characterized by intermittent skin rippling, ITSMCS presents a diagnostic challenge.
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