Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Fixed Action Patterns01:06

Fixed Action Patterns

A fixed action pattern (FAP) is a specific, hard-wired sequence of behaviors that occurs in response to an external stimulus, called a sign stimulus. The behavior is “fixed” because it is essentially unchangeable—proceeding similarly across individuals of a species every time it occurs.
Position-effect Variegation02:32

Position-effect Variegation

In 1928, a German botanist Emil Heitz observed the moss nuclei with a DNA binding dye. He observed that while some chromatin regions decondense and spread out in the interphase nucleus, others do not. He termed them euchromatin and heterochromatin, respectively. He proposed that the heterochromatin regions reflect a functionally inactive state of the genome. It was later confirmed that heterochromatin is transcriptionally repressed, and euchromatin is transcriptionally active chromatin.
Mechanism of Lamellipodia Formation01:31

Mechanism of Lamellipodia Formation

Cells migrating in response to external stimuli form lamellipodia, which are thin membrane protrusions supported by a mesh of linked, branched, or unbranched actin filaments. These actin filaments interact with myosin motor proteins, creating the dynamic actomyosin complex within the cytoskeleton. Contractility, or the ability to generate contractile stress, is inherent to the actomyosin complex. It helps cells detect the stiffness of the surrounding ECM and exert contractile force for...
Cell Polarization by Rho Proteins01:21

Cell Polarization by Rho Proteins

Cell polarity is the asymmetric distribution of cellular and membrane components, making one side of the cell different from the other. This polarity is essential to many processes such as embryogenesis, axon migration, glucose transport across epithelial cells, and directional cell migration. A migrating cell responds to intracellular or extracellular signals via molecular cascades that reorganize the actin cytoskeleton to establish this polarity. In these cells, the Rho family proteins Cdc42,...
Mechanism of Ciliary Motion01:05

Mechanism of Ciliary Motion

The ciliary structures were first seen in 1647 by Antonie Leeuwenhoek while observing the protozoans. In lower organisms, these appendages are responsible for cell movement, while in higher organisms, these appendages help in the movement of the extracellular fluids within the body cavities.
The cilia are made up of microtubules in a 9+2 arrangement, with nine microtubule doublet ring bundles, surrounding a pair of central singlet microtubule bundles. The doublet microtubule bundles are...
Gestalt Principles of Perception01:21

Gestalt Principles of Perception

Gestalt principles provide a framework for understanding how humans perceive objects as unified wholes within their context. These principles are essential in explaining the cognitive processes that make sense of complex visual stimuli by organizing them into coherent groups. One fundamental principle is proximity, which posits that objects located close to each other are perceived as a collective group. For instance, when dots are positioned near one another, the visual system interprets them...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Application of AI in Cancer MDT and its Legal Implication.

Clinical oncology (Royal College of Radiologists (Great Britain))·2026
Same author

Bovine TB infection status in cattle in Great Britain in 2024.

The Veterinary record·2026
Same author

Guy's Cancer Cohort: Guy's Cancer Centre's Real-World Evidence Programme 5 years later.

ESMO real world data and digital oncology·2026
Same author

Mineralogical evidence for hydrothermal alteration of Bennu samples.

Nature geoscience·2025
Same author

SCQOLIT-SF: A revised outcome measure for assessing patient-reported outcomes in non-melanoma skin cancers.

Journal of plastic, reconstructive & aesthetic surgery : JPRAS·2025
Same author

Correction: Introduction and validation of the open symptom framework: a public domain modular framework for patient-reported measurement of symptoms related to cancer and its treatment.

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation·2024

Related Experiment Video

Updated: Jul 19, 2026

High-resolution Patterning Using Two Modes of Electrohydrodynamic Jet: Drop on Demand and Near-field Electrospinning
09:16

High-resolution Patterning Using Two Modes of Electrohydrodynamic Jet: Drop on Demand and Near-field Electrospinning

Published on: July 10, 2018

Mechanisms of ordering in striped patterns.

C Harrison1, D H Adamson, Z Cheng

  • 1Department of Physics, Princeton Materials Institute, Princeton University, Princeton, NJ 08544, USA.

Science (New York, N.Y.)
|November 25, 2000
PubMed
Summary

We studied how striped patterns in block copolymer thin films order. The main finding is that multiple disclinations annihilate together, which is key for understanding pattern formation and block copolymer lithography.

More Related Videos

Scalable Stamp Printing and Fabrication of Hemiwicking Surfaces
06:16

Scalable Stamp Printing and Fabrication of Hemiwicking Surfaces

Published on: December 18, 2018

Elaborate Control of Inkjet Printer for Fabrication of Chip-based Supercapacitors
10:57

Elaborate Control of Inkjet Printer for Fabrication of Chip-based Supercapacitors

Published on: November 30, 2021

Related Experiment Videos

Last Updated: Jul 19, 2026

High-resolution Patterning Using Two Modes of Electrohydrodynamic Jet: Drop on Demand and Near-field Electrospinning
09:16

High-resolution Patterning Using Two Modes of Electrohydrodynamic Jet: Drop on Demand and Near-field Electrospinning

Published on: July 10, 2018

Scalable Stamp Printing and Fabrication of Hemiwicking Surfaces
06:16

Scalable Stamp Printing and Fabrication of Hemiwicking Surfaces

Published on: December 18, 2018

Elaborate Control of Inkjet Printer for Fabrication of Chip-based Supercapacitors
10:57

Elaborate Control of Inkjet Printer for Fabrication of Chip-based Supercapacitors

Published on: November 30, 2021

Area of Science:

  • Materials Science
  • Polymer Science
  • Soft Matter Physics

Background:

  • Block copolymers form ordered microdomain patterns in thin films.
  • Understanding the dynamics of these patterns is crucial for applications like nanolithography.
  • Disclinations are topological defects that influence pattern ordering.

Purpose of the Study:

  • To investigate the ordering dynamics of cylindrical block copolymer microdomains in a thin film.
  • To identify the dominant mechanism of disclination annihilation during annealing.
  • To understand the role of topological constraints on pattern evolution.

Main Methods:

  • Time-lapse atomic force microscopy was used to track disclinations.
  • Annealing was performed to induce ordering.
  • Analysis of kinetic scaling laws was conducted.

Main Results:

  • A dominant mechanism of disclination annihilation involving three or four disclinations (quadrupoles) was observed.
  • Pairwise disclination annihilation events were suppressed due to topological constraints.
  • Observed kinetic scaling laws support multi-disclination annihilation events.

Conclusions:

  • The study reveals key insights into the ordering dynamics of block copolymer patterns.
  • Topological constraints significantly influence defect annihilation mechanisms.
  • Findings contribute to the understanding of two-dimensional pattern formation and block copolymer lithography applications.