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Risk Factors for Breast Cancer among Japanese Women: A Case-Control Study in Ibaraki, Japan
1Graduate School of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan.
Breast Cancer (Tokyo, Japan)
|November 25, 2000
Summary
This study found that lifestyle factors like smoking and higher body mass index increase breast cancer risk in Japanese women. However, physical activity and hot baths may reduce risk, suggesting potential for prevention.
Area of Science:
- Epidemiology
- Oncology
- Public Health
Background:
- Limited epidemiologic data on breast cancer risk factors in Japanese women.
- Need to clarify associations between lifestyle, body size, and breast cancer risk.
Purpose of the Study:
- To investigate the relationship between lifestyle, body size, and breast cancer risk in Japanese women.
- To identify potential modifiable risk and protective factors for breast cancer.
Main Methods:
- Matched case-control study in Ibaraki, Japan (148 cases, 296 controls).
- Data collected via self-administered questionnaire on lifestyle, body size, and medical history.
- Conditional logistic regression used to estimate odds ratios (ORs) and 95% confidence intervals (95% CI).
Main Results:
- Increased breast cancer risk associated with higher body mass index and heavy weight in postmenopausal women.
- Current or ex-smokers showed a significantly increased risk (OR = 3.33).
- Recreational physical activity was linked to a reduced risk (OR = 0.36), and hot baths showed a decreased risk (OR = 0.67).
- Taller women had a slightly increased risk (OR = 1.49).
- No significant association found between alcohol consumption and breast cancer risk.
Conclusions:
- Potentially modifiable lifestyle factors, including physical activity and smoking cessation, may play a role in breast cancer prevention.
- Findings highlight the importance of lifestyle modifications for reducing breast cancer incidence in Japanese women.
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