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Use of Galleria mellonella as a Model Organism to Study Legionella pneumophila Infection
Published on: November 22, 2013
Legionella
1Infectious Disease Service, Summa Health System, 75 Arch Street, Suite 105, Akron, OH 44304, and Northeastern Ohio Universities College of Medicine, Rootstown, OH, USA.
Abstract:
Since the identification of Legionella two decades ago, a vast amount of information has accumulated concerning the microbiology, clinical manifestations, and therapy of infections due to these organisms. There are now more than 40 species of Legionella identified. The spectrum of legionellosis ranges from asymptomatic infection to serious pneumonia. Two clinical syndromes have been identified: Legionnaire's disease and Pontiac fever. Recent information suggests that the newer macrolides and newer fluoroquinolones are preferred therapy for serious disease.
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