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Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis
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Fungal Infections of the Lung.
1Infectious Diseases Section, New York Veterans Affairs Medical Center, 423 East 23rd Street, New York, NY 10010, USA.
Current Infectious Disease Reports
|November 30, 2000
Summary
Fungal lung infections are increasingly common. Recent advances have improved understanding of their epidemiology, clinical course, and treatment with new antifungal medications.
Area of Science:
- Medical Mycology
- Pulmonology
- Infectious Diseases
Background:
- Fungal pulmonary infections are a growing clinical concern.
- Both endemic and opportunistic fungi are significant pathogens.
- Recent years have seen advances in understanding fungal lung disease.
Purpose of the Study:
- To review endemic and opportunistic fungal pulmonary pathogens.
- To highlight recent therapeutic advances in treating fungal lung infections.
- To provide an updated perspective on the clinical management of pulmonary mycoses.
Main Methods:
- Literature review of recent studies on fungal pulmonary pathogens.
- Analysis of epidemiological data for fungal lung infections.
- Evaluation of clinical outcomes and treatment strategies for fungal pneumonia.
Main Results:
- Fungal pathogens are increasingly recognized in pulmonary disease.
- Newer triazoles and lipid formulations of amphotericin B show therapeutic promise.
- Improved understanding of fungal disease epidemiology and clinical course.
Conclusions:
- Fungal pulmonary infections require ongoing attention and research.
- Advances in antifungal therapy are improving patient outcomes.
- Comprehensive review aids clinicians in managing fungal lung diseases.
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