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Benign hyperthermia following prolonged TIVA with propofol
H Fukayama1, H Kohase, M Umino
1Department of Anesthesiology, Graduate School, Tokyo Medical and Dental University, Japan. fukayama.dane@dent.tmd.ac.jp
Canadian Journal of Anaesthesia = Journal Canadien D'Anesthesie
|November 30, 2000
Summary
Propofol anesthesia can cause transient hyperthermia in some patients, particularly when combined with hypotensive techniques. Careful monitoring of anesthetic depth is crucial to prevent this side effect.
Area of Science:
- Anesthesiology
- Pharmacology
Background:
- Propofol is a common anesthetic agent known for rapid onset and recovery.
- Its use in major surgeries, like facial reconstructive procedures, is well-established.
Observation:
- Four patients undergoing facial surgery experienced a rise in body temperature (>38°C) towards the end of anesthesia.
- This hyperthermia occurred despite normal preoperative temperatures and interventions like cooling blankets and fluids.
Findings:
- The hyperthermia was potentially linked to continuous propofol infusion and tri-nitro-glycerin-induced hypotension, possibly masking lighter anesthesia.
- The elevated temperatures resolved postoperatively without complications.
Implications:
- Anesthesiologists should be vigilant for hyperthermia during propofol anesthesia, especially with concurrent hypotensive strategies.
- Maintaining optimal anesthetic depth is essential to avoid adverse events.