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Published on: May 2, 2017
Environmental enrichment-related injury in a macaque (Macaca fascicularis): intestinal linear foreign body
1Office of Laboratory Animal Care, University of California, Berkeley 94720-7150, USA.
Abstract:
A three-year old male cynomolgus macaque (Macaca fascicularis) presented with clinical signs of anorexia and depression that decreased over a 48-hour period. Results of abdominal radiography abdominocentesis, blood biochemical analysis and CBC suggested septic peritonitis. Exploratory laparotomy revealed multiple perforations along the mesenteric border of the small intestine. Necropsy revealed masses of fibrous material in the stomach and cecum. Multiple mucosal ulcerations, as well as linear fibrous material, were found in the small intestine. The ulceration, perforations, and septic peritonitis were attributed to the ingestion of rope that had been attached to the animal's cage as an environmental-enrichment device.
Insights
A young macaque ingested rope, leading to severe gastrointestinal issues including perforations and septic peritonitis. This case highlights the dangers of environmental enrichment devices in non-human primates.
Area of Science:
- Veterinary Medicine
- Primate Medicine
- Toxicology
Background:
- Environmental enrichment is crucial for captive non-human primate welfare.
- Careful selection and monitoring of enrichment materials are necessary to prevent accidental ingestion.
- Cynomolgus macaques (Macaca fascicularis) are susceptible to gastrointestinal complications.
Observation:
- A three-year-old male cynomolgus macaque exhibited anorexia and depression.
- Clinical signs progressed over 48 hours, suggesting a critical health event.
- Diagnostic imaging and laboratory tests indicated septic peritonitis.
Findings:
- Exploratory laparotomy revealed multiple small intestine perforations.
- Necropsy identified fibrous material in the stomach and cecum.
- Small intestine exhibited ulcerations and linear fibrous material, consistent with rope ingestion.
Implications:
- Accidental ingestion of environmental enrichment devices can cause life-threatening gastrointestinal perforations.
- Veterinary professionals must consider foreign body ingestion when diagnosing non-human primates with acute abdominal signs.
- Risk assessment of enrichment materials is vital to ensure animal safety and welfare.
Related Concept Videos
Intestinal Obstruction I: Introduction
Intestinal Obstruction II: Pathophysiology

