Related Experiment Videos
Infantile colic: crying time reduction with a whey hydrolysate: A double-blind, randomized, placebo-controlled trial
P L Lucassen1, W J Assendelft, J W Gubbels
1Institute for Research in Extramural Medicine, Vrije Universiteit, Amsterdam, the Netherlands.
Pediatrics
|January 11, 2000
Summary
Whey hydrolysate formula significantly reduced crying time in colicky infants. This study found a daily reduction of 63 minutes in crying duration for infants treated with this specialized formula.
Area of Science:
- Pediatrics
- Gastroenterology
- Clinical Nutrition
Background:
- Infantile colic is a common condition affecting healthy infants.
- Current management strategies for infantile colic are limited.
- Specialized infant formulas are explored for managing colic symptoms.
Purpose of the Study:
- To evaluate the efficacy of whey hydrolysate formula in treating infantile colic.
- To assess the impact of whey hydrolysate formula on crying duration in primary care.
Main Methods:
- A randomized, double-blind, parallel trial was conducted.
- Forty-three formula-fed infants (<6 months) with colic were enrolled.
- Infants received either whey hydrolysate or standard formula for one week.
Main Results:
- Whey hydrolysate formula led to a mean reduction of 63 minutes in daily crying time.
- This reduction was statistically significant compared to standard formula.
- No significant subgroup differences were observed due to study scope.
Conclusions:
- Extensively hydrolyzed whey formula is an effective intervention for infantile colic.
- Whey hydrolysate formula can reduce crying duration in a primary care setting.
- Further research may explore long-term effects and specific subpopulations.