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Updated: Aug 13, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
Neurological bases of behavioral development in infancy
1Department of Pediatrics, University of Bern, Pourtalèsstrasse 57, 3074 Muri, Bern, Switzerland. norbert.herschkowitz@pupk.unibe.ch
Early childhood development involves key psychological milestones in the first two years, linked to significant brain changes. These include memory improvements, fear development, language acquisition, and self-awareness, all supported by evolving brain structures and connectivity.
Area of Science:
- Developmental psychology
- Neuroscience
- Child development
Background:
- The first two years of life are critical for psychological and brain development.
- Understanding the interplay between cognitive milestones and neural changes is essential.
Purpose of the Study:
- To outline key psychological competences emerging in the first two years of life.
- To correlate these behavioral changes with structural, biochemical, and physiological brain alterations.
Main Methods:
- Review of developmental psychology literature.
- Correlation analysis between behavioral events and neurobiological changes.
- Focus on the first two years of postnatal development.
Main Results:
- First year: loss of neonatal reflexes, improved memory, stranger/separation anxiety linked to cortical inhibition, prefrontal cortex/hippocampus maturation, and limbic system connections.
- Second year: language explosion and self-awareness emerge, dependent on inference and linked to interhemispheric connectivity, prefrontal cortex, and cortical-subcortical network maturation.
Conclusions:
- Psychological development in infancy is closely tied to specific, measurable brain maturation processes.
- The brain's structural and functional changes provide the foundation for emerging cognitive and emotional abilities.
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