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Maternal and cord plasma selenium levels in full-term neonates
G Gathwala1, O P Yadav, I Singh
1Department of Pediatrics, Pt. B.D.S. Postgraduate Institute of Medical Sciences, Rohtak.
Indian Journal of Pediatrics
|December 6, 2000
Summary
Neonatal selenium nutrition is crucial for preventing oxygen free radical damage. This study found significantly lower plasma selenium levels in newborns compared to their mothers at delivery.
Area of Science:
- Biochemistry
- Neonatal Nutrition
- Trace Elements
Background:
- Selenium is an essential trace element vital for antioxidant defense, particularly through glutathione peroxidase.
- Adequate selenium nutrition is critical for neonates due to their vulnerability to oxidative stress.
Purpose of the Study:
- To evaluate and compare plasma selenium levels in full-term neonates and their mothers.
- To investigate the correlation between maternal health factors (e.g., anemia) and neonatal selenium status.
Main Methods:
- Plasma selenium concentrations were measured in 82 pairs of mothers and their full-term neonates at delivery.
- Maternal hemoglobin levels were assessed to identify anemia (Hb < 8 g/dl).
Main Results:
- Neonates exhibited significantly lower plasma selenium levels (54.17 ± 1.34 ppb) compared to their mothers (70.63 ± 1.62 ppb).
- Mothers with anemia (Hb < 8 g/dl) had lower plasma selenium levels (60.74 ± 4.57 ppb) than non-anemic mothers (74.19 ± 2.17 ppb).
- Maternal age, parity, literacy, and socioeconomic status did not significantly influence plasma selenium levels.
Conclusions:
- Newborns may have suboptimal selenium status at birth, necessitating attention to maternal selenium intake during pregnancy.
- Maternal anemia is associated with reduced selenium levels, highlighting a potential link between maternal health and neonatal nutrient status.