Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

"FUR"--one size suits all.

M Rutland1, L Que, I M Hassan

  • 1Department of Nuclear Medicine, Auckland Hospital, New Zealand.

European Journal of Nuclear Medicine
|December 6, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pharmacogenetics of medication-related osteonecrosis of the jaw: a systematic review and meta-analysis.

International journal of oral and maxillofacial surgery·2019
Same author

Novel inactivating mutation of the calcium-sensing receptor in a young woman with mild hypercalcaemia.

Internal medicine journal·2014
Same author

Bhutan: from the Mediaeval to the millennium.

Asian affairs·2010
Same author

Mixtures of n-dodecyl-beta-D-maltoside and hexaoxyethylene dodecyl ether--surface properties, bulk properties, foam films, and foams.

Advances in colloid and interface science·2010
Same author

Acid-stress-induced changes in enterohaemorrhagic Escherichia coli O157 : H7 virulence.

Microbiology (Reading, England)·2009
Same author

Forces between Two Glass Surfaces with Adsorbed Hexadecyltrimethylammonium Salicylate.

Langmuir : the ACS journal of surfaces and colloids·2009
Same journal

[Not Available].

European journal of nuclear medicine·2016
Same journal

A Window on Latin America.

European journal of nuclear medicine·2016
Same journal

Erratum: Eur J Nucl Med (1999) 26: 686-692.

European journal of nuclear medicine·2016
Same journal

Nuclear medicine in the next decade.

European journal of nuclear medicine·2014
Same journal

Erratum: Impact of attenuation correction on the accuracy of FDG-PET in patients with abdominal tumors: a free-response ROC analysis.

European journal of nuclear medicine·2014
Same journal

(99m)Tc(V)DMSA quantitatively predicts (188)Re(V)DMSA distribution in patients with prostate cancer metastatic to bone.

European journal of nuclear medicine·2014
See all related articles

Organ function, measured by fractional uptake rate (FUR) using tracer kinetics, is independent of patient size or gender in adults with normal organ function. This method offers a reliable way to assess organ health across diverse body types.

Area of Science:

  • Nuclear Medicine
  • Radiopharmacology
  • Physiology

Background:

  • Assessing organ function is crucial in clinical practice.
  • Patient size and gender can influence physiological measurements.
  • Tracer kinetics offers a quantitative method for evaluating organ function.

Purpose of the Study:

  • To determine if organ function, assessed via tracer kinetics, is independent of patient size and gender.
  • To validate the fractional uptake rate (FUR) as a universal metric for organ function.

Main Methods:

  • Amalgamated data from previous dynamic gamma camera studies.
  • Calculated fractional uptake rate (FUR) using Rutland-Patlak plot analysis.
  • Analyzed FUR values across subgroups stratified by patient size and gender.

Related Experiment Videos

Main Results:

  • No significant differences in FUR values were observed between subgroups based on patient size.
  • No significant differences in FUR values were observed between male and female subgroups.
  • FUR demonstrated independence from patient size and gender in adults with normal organ function.

Conclusions:

  • Fractional uptake rate (FUR) is a robust, size- and gender-independent measure of organ function in individuals with normal organ function.
  • FUR is particularly valuable for assessing organ function in patients with atypical body sizes, such as children.