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Experimental kerosene poisoning in goats
M R Aslani1, A R Movassaghi, M Mohri
1Department of Clinical Studies, School of Veterinary Medicine, Ferdowsi University of Mashhad, Iran.
Veterinary and Human Toxicology
|December 9, 2000
Summary
Kerosene ingestion in goats causes dose-dependent toxicity. High doses (40 ml/kg) led to severe poisoning, mortality, and significant postmortem findings like gangrenous pneumonia and brain edema.
Area of Science:
- Veterinary Toxicology
- Animal Health
- Toxicology
Background:
- Kerosene is a common household and industrial substance.
- Accidental ingestion can occur in livestock, posing a risk to animal health.
- Understanding the toxic effects of kerosene in goats is crucial for veterinary emergency response.
Purpose of the Study:
- To evaluate the toxic effects and lethal dose of kerosene in young goats.
- To document clinical signs and postmortem findings associated with kerosene poisoning in goats.
Main Methods:
- Eighteen young goats were divided into three groups.
- Single oral doses of kerosene (10, 20, or 40 ml/kg body weight) were administered.
- Clinical signs and mortality were monitored over time.
- Postmortem examinations were conducted on deceased animals.
Main Results:
- Low doses (10, 20 ml/kg) caused mild to moderate clinical signs with no mortality.
- The high dose (40 ml/kg) resulted in severe poisoning, characterized by bloat, coughing, vomiting, respiratory distress, and neurological signs.
- Mortality occurred within 4 hours to 11 days in the high-dose group.
- Postmortem findings included gangrenous pneumonia, pleuropneumonia, brain congestion, edema, and kidney nephrosis.
Conclusions:
- Kerosene exhibits dose-dependent toxicity in goats.
- High-dose kerosene ingestion is fatal and causes severe pathological changes, particularly affecting the respiratory system and brain.
- Veterinary intervention is critical for managing kerosene poisoning in goats.