Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Radical prostatectomy: options and issues.

H Huland1

  • 1University Hospital Eppendorf, Hamburg, Germany.

European Urology
|December 15, 2000
PubMed
Summary
This summary is machine-generated.

Radical prostatectomy can be effective for localized prostate cancer. Identifying patients who benefit most, considering potency and continence outcomes, is crucial for treatment decisions.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Quality criteria in urology : How to obtain comparable results?]

Der Urologe. Ausg. A·2021
Same author

Early clinical experience with water-jet dissection (hydro-jet) during nerve-sparing radical retropubic prostatectomy.

Minimally invasive therapy & allied technologies : MITAT : official journal of the Society for Minimally Invasive Therapy·2017
Same author

[Not Available].

Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]·2016
Same author

[Systematic analysis of treatment results as a quality control instrument using the example of a large European center].

Der Urologe. Ausg. A·2015
Same author

["Expanded prostate cancer index composite" (EPIC-26): Results of functional treatment in patients with localized prostate cancer].

Der Urologe. Ausg. A·2015
Same author

Adherence of the indication to European Association of Urology guideline recommended pelvic lymph node dissection at a high-volume center: Differences between open and robot-assisted radical prostatectomy.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2015
Same journal

Re: Twelve-month Results from the CISTO Study Comparing Radical Cystectomy Versus Bladder-sparing Therapy for Recurrent High-grade Non-muscle-invasive Bladder Cancer: Recurrent High-risk NMIBC: One Bladder, Choose Wisely.

European urology·2026
Same journal

Re: Dries Develtere, Riccardo Bertolo. Cumulative Genitourinary Toxicity After Prostate Radiotherapy: High-Level Long-Term Randomized Evidence. J Clin Oncol. Online ahead of print. http://dx.doi.org/10.1200/JCO-26-00436.

European urology·2026
Same journal

In Memory of Paul Mitrofanoff (1934-2025).

European urology·2026
Same journal

Re: McKay RR, Pal S, Xie W, et al. Advanced Urologic Cancer Consensus Conference (AUC3) 2025: Expert Consensus on the Management of Renal Cell and Urinary Tract Cancers. CA Cancer J Clin 2026;76:e70052.

European urology·2026
Same journal

Re: Ultra-hypofractionated Stereotactic Ablative Body Radiotherapy for Primary Renal Cell Carcinoma: 5-year Outcomes from a Pooled Analysis of the FASTRACK Trials.

European urology·2026
Same journal

Re: Alexander D. Sherry, Van To, Criselle D'souza, et al. Metastasis-directed Therapy With or Without Pembrolizumab for Oligometastatic Clear Cell Renal Cell Carcinoma: Pooled Analysis of Two Prospective Single-arm Phase 2 Trials. Eur Urol. In press. http://dx.doi.org/10.1016/j.eururo.2026.03.024.

European urology·2026
See all related articles

Area of Science:

  • Urology
  • Oncology
  • Pathology

Background:

  • Radical prostatectomy is a standard treatment for localized prostate cancer.
  • Some patients experience post-operative incontinence and potency loss.
  • Identifying suitable candidates for radical prostatectomy is a clinical challenge.

Purpose of the Study:

  • To review the natural history of localized prostate cancer.
  • To identify factors influencing treatment decisions for individual patients.
  • To explore predictive models for radical prostatectomy outcomes.

Main Methods:

  • Review of natural history data for localized prostate cancer.
  • Analysis of pathological features, including Gleason grade 4/5 tumor quantity.
  • Application of Classification and Regression Trees (CART) analysis for predictive modeling.

Related Experiment Videos

Main Results:

  • T1/T2 prostate tumors exhibit heterogeneity in pathological stage and outcomes.
  • The quantity of Gleason grade 4/5 tumor is a significant prognostic factor for lymph node progression and capsular penetration.
  • CART analysis can predict pT2 tumor probability, informing nerve-sparing radical prostatectomy candidacy.

Conclusions:

  • Accurate patient selection for radical prostatectomy is essential to optimize outcomes.
  • Preoperative parameters, particularly Gleason grade 4/5 tumor quantity, aid in predicting treatment response.
  • Nerve-sparing radical prostatectomy offers improved potency and continence when feasible.