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Regulation of sigma factor activity during Bacillus subtilis development
1Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI 48824, USA. kroos@pilot.msu.edu
Current Opinion in Microbiology
|December 21, 2000
Abstract:
Progression of Bacillus subtilis through a series of morphological changes is driven by a cascade of sigma (sigma) factors and results in formation of a spore. Recent work has provided new insights into the location and function of proteins that control sigma factor activity, and has suggested that multiple mechanisms allow one sigma factor to replace another in the cascade.