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Intermittent explosive disorder.

E F Coccaro1

  • 1Clinical Neuroscience and Psychopharmacology Research Unit, The Pritzker School of Medicine, The University of Chicago, 5841 South Maryland Avenue, Chicago, IL 60637, USA. ecoccaro@yoda.bsd.uchicago.edu

Current Psychiatry Reports
|December 21, 2000
PubMed
Summary
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Intermittent explosive disorder (IED) is characterized by recurrent impulsive aggressive outbursts. New research criteria may facilitate empirical studies on its genetics, biology, and treatment.

Area of Science:

  • Psychiatry
  • Neuroscience
  • Behavioral Science

Background:

  • Intermittent explosive disorder (IED) is defined as recurrent, problematic impulsive aggressive behavior.
  • Diagnostic challenges have historically hindered systematic research into IED.
  • Recent advancements in research criteria offer potential for empirical investigation.

Purpose of the Study:

  • To review the history and diagnostic criteria of IED.
  • To explore the phenomenologic, epidemiologic, genetic, biologic, and treatment aspects of IED.
  • To highlight the importance of applying existing research on impulsive aggression to IED.

Main Methods:

  • Literature review of IED history and diagnostic evolution.
  • Synthesis of research on impulsive aggression correlates.

Related Experiment Videos

  • Analysis of new research criteria for IED.

    • Main Results:

    • IED is conceptualized as a distinct expression of impulsive aggression.
    • New research criteria are proposed to enable empirical study.
    • Existing knowledge on impulsive aggression provides a foundation for IED research.

    Conclusions:

    • IED research is advancing due to updated diagnostic criteria.
    • Understanding the genetics, biology, and treatment of impulsive aggression is key to advancing IED knowledge.
    • Further empirical work is crucial for a comprehensive understanding of IED.