Related Experiment Video
Updated: Aug 4, 2026

A Step by Step Protocol for Subretinal Surgery in Rabbits
Published on: September 13, 2016
Open retinotomy after submacular surgery
B A Cooper1, M A Thomas, N M Holekamp
1Department of Ophthalmology, Washington University, St. Louis, Missouri, USA.
Purpose:
To report persistent open retinotomy after submacular surgery in patients with presumed ocular histoplasmosis.
Methods:
Retrospective review. Five eyes of 5 patients with submacular choroidal neovascularization associated with presumed ocular histoplasmosis had pars plana vitrectomy, detachment of the posterior hyaloid, and surgical removal of the neovascular complex using the small retinotomy technique. All eyes were followed postoperatively for a mean of 47 months (range, 36 to 73 months).
Results:
In all 5 patients, the open retinotomy persisted after submacular surgery. No complications were associated with the presence of an open retinotomy.
Conclusion:
Persistence of the retinotomy site may occur after submacular surgery. With follow-up of at least 36 months, no significant complication is associated with an open retinotomy site.

