Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Peptic disease in elderly patients.

N Khaghan1, P R Holt

  • 1Department of Medicine, St Luke's/Roosevelt Hospital Center, New York, New York 10025, USA

Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie
|December 23, 2000
PubMed
Summary

As people live longer, gastrointestinal issues like peptic ulcer disease require more focus in older adults. This review covers physiological changes, Helicobacter pylori

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Celecoxib does not alter intestinal microbiome in a longitudinal diet-controlled study.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2016
Same author

Cox-2 is needed but not sufficient for apoptosis induced by Cox-2 selective inhibitors in colon cancer cells.

Apoptosis : an international journal on programmed cell death·2004
Same author

Comparison of calcium supplementation or low-fat dairy foods on epithelial cell proliferation and differentiation.

Nutrition and cancer·2002
Same author

p21(WAF1/cip1) is an important determinant of intestinal cell response to sulindac in vitro and in vivo.

Cancer research·2001
Same author

Diarrhea and malabsorption in the elderly.

Gastroenterology clinics of North America·2001
Same author

25-hydroxyvitamin D-1alpha-hydroxylase in normal and malignant colon tissue.

Lancet (London, England)·2001

Area of Science:

  • Gastroenterology and Geriatric Medicine

Background:

  • Increasing life expectancy highlights the need to address age-related gastrointestinal health issues.
  • Peptic ulcer disease (PUD) is a significant concern in the elderly population due to physiological changes and comorbidities.

Purpose of the Study:

  • To review the physiological alterations contributing to peptic ulcer disease in elderly patients.
  • To examine the impact of Helicobacter pylori infection on PUD in older individuals.
  • To discuss diagnostic and therapeutic modifications for PUD in the geriatric population.

Main Methods:

  • Literature review of physiological changes affecting the gastrointestinal system in the elderly.
  • Analysis of studies on Helicobacter pylori infection and its role in PUD.
  • Examination of clinical presentations, diagnostic approaches, and treatment strategies for PUD in older adults.

Main Results:

  • Elderly patients exhibit distinct physiological changes that increase PUD susceptibility.
  • Helicobacter pylori infection complicates PUD management in older individuals.
  • Atypical symptom presentation is common in elderly PUD patients, necessitating thorough evaluation.
  • Standard diagnostic and treatment protocols may require adjustments for elderly patients.

Conclusions:

  • Age-related physiological changes and Helicobacter pylori infection significantly influence peptic ulcer disease in the elderly.
  • Early and aggressive endoscopic evaluation is crucial for accurate diagnosis in this demographic.
  • Treatment strategies, including H2 receptor antagonists, proton pump inhibitors, and H. pylori eradication, need careful tailoring for elderly patients.

Related Experiment Videos