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PediaSure in the treatment of severe malnutrition in Pakistani children

D S Akram1, F Y Bharmal, T Hussain

  • 1Department of Paediatrics, Unit-I, Civil Hospital, Karachi.

JPMA. the Journal of the Pakistan Medical Association
|December 29, 2000
PubMed

Insights

PediaSure effectively supports nutrition therapy in malnourished children, leading to significant weight gain and improved caloric intake within two weeks. This high-density feed is well-tolerated and aids in the initial rehabilitation phase.

Area of Science:

  • Pediatric Nutrition
  • Clinical Nutrition
  • Malnutrition Rehabilitation

Background:

  • Severe malnutrition in children presents significant health challenges.
  • Effective nutritional intervention is crucial for recovery and growth.
  • Early-stage rehabilitation requires specialized, high-caloric nutritional support.

Purpose of the Study:

  • To evaluate the efficacy of PediaSure as a primary calorie source for severely malnourished children.
  • To assess the impact of PediaSure on weight gain and nutritional status during the initial two weeks of rehabilitation.
  • To monitor clinical tolerance and biochemical parameters during PediaSure supplementation.

Main Methods:

  • A study involving 31 severely malnourished children aged 1-5 years.
  • PediaSure was administered as the sole calorie source for two weeks post-acute complication management.
  • Monitoring included weight gain, clinical tolerance, stool output, and hematological/biochemical parameters.

Main Results:

  • Significant increase in caloric intake (p < 0.01) and weight gain (average 7.5 gm/kg/day).
  • Improved Z-score for weight-for-age (p < 0.01) over the two-week period.
  • High tolerance for PediaSure with no significant adverse biochemical imbalances or diarrhea observed.

Conclusions:

  • PediaSure is an effective nutritional therapy for the initial stage of rehabilitation in severely malnourished children.
  • The high-density caloric feed supports significant weight gain and nutritional improvement.
  • PediaSure demonstrates excellent clinical tolerance and safety in this vulnerable population.
Abstract

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