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Extracellularly truncated desmoglein 1 compromises desmosomes in MDCK cells

N Serpente1, C Marcozzi, G A Roberts

  • 1Division of Membrane Biology, National Institute for Medical Research, Ridgeway, Mill Hill, London NW7 1AA, UK.

Molecular Membrane Biology
|December 29, 2000
PubMed
Summary

The extracellular domain of desmoglein 1 (Dsg1) is crucial for epithelial tissue stability. Deleting this domain disrupts desmosome formation and cell adhesion, impacting tissue integrity.

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