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Glycosidic flavonoids as rat-liver injury preventing compounds from green tea
1Department of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University, Japan.
Bioscience, Biotechnology, and Biochemistry
|December 29, 2000
Abstract:
A glycosidic flavonoids-rich fraction from green tea leaves was purified to isolate five glycosidic flavonoids, guided by the detection of a preventive effect on D-galactosamine-induced liver injury in rats. These were identified as a flavone C-glycoside (1) and trisaccharide flavonols (2-5) based on the spectroscopic analyses. These compounds suppressed the D-galactosamine-induced increase of plasma alanine aminotransferase and asparatate aminotransferase activities in rats.