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Updated: Jun 28, 2026

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy
Published on: September 20, 2024
Surgeon's perspective in intractable childhood epilepsy
1Department of Neurosurgery, Neurosciences Centre, All India Institute of Medical Sciences, New Delhi.
Insights
Pediatric epilepsy surgery is gaining traction due to the developing brain's plasticity and the risks of uncontrolled seizures. Early surgical intervention offers excellent outcomes and potential cures for carefully selected children with partial seizures.
Area of Science:
- Pediatric Neurology
- Neurosurgery
- Epileptology
Background:
- Growing interest in surgical epilepsy management for children over the past two decades.
- Recognition of the developing brain's plasticity and the detrimental effects of uncontrolled seizures.
- Prompting earlier surgical intervention when indicated for pediatric epilepsy.
Purpose of the Study:
- To highlight the importance and process of surgical management for pediatric epilepsy.
- To outline the comprehensive presurgical evaluation required for potential surgical candidates.
- To emphasize the critical role of multidisciplinary teams in successful epilepsy surgery programs.
Main Methods:
- Detailed neurological evaluation.
- Electroencephalography (EEG) and video EEG monitoring.
- High-resolution Magnetic Resonance Imaging (MRI) and Single-Photon Emission Computed Tomography (SPECT).
- Neuropsychological evaluation.
Main Results:
- Properly selected epilepsy cases demonstrate excellent surgical outcomes.
- Epilepsy surgery offers the possibility of a cure for pediatric patients.
- Successful implementation requires close coordination among a multidisciplinary team.
Conclusions:
- Surgical management is an increasingly viable option for pediatric epilepsy.
- Comprehensive presurgical evaluation is crucial for patient selection.
- Multidisciplinary team collaboration is essential for optimal results in pediatric epilepsy surgery programs.
Abstract:
There is increased interest in the surgical management of epilepsy in children in the last decade or two. The plasticity of the developing brain and realization of the deleterious effects of uncontrolled seizures on the brain have prompted earlier surgery where indicated. All patients with uncontrolled partial seizures are potential candidates for surgery and merit a detailed presurgical evaluation. This consists of a detailed neurological evaluation, EEG, video EEG, a high resolution MRI, SPECT, and a neuropsychological evaluation. The outcome of properly selected cases for surgery is excellent and it offers the possibility of a cure. However, close coordination of a multidisciplinary team is essential for the successful implementation of any epilepsy surgery program.
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