Related Experiment Videos
A lysosomal protease enters the death scene
1The Burnham Institute, 10901 North Torrey Pines Road, La Jolla, California 92037, USA. gsalvesen@burnham.org
The Journal of Clinical Investigation
|January 3, 2001
Summary
No abstract available in PubMed .
Related Concept Videos
Articles linked to this work by shared authors, journal, and citation graph.
Unnatural amino acids increase sensitivity and provide for the design of highly selective caspase substrates.
Cell death and differentiation·2014
Intrinsic cleavage of receptor-interacting protein kinase-1 by caspase-6.
Cell death and differentiation·2012
Enzymatically active single chain caspase-8 maintains T-cell survival during clonal expansion.
Cell death and differentiation·2010
Activation mechanism and substrate specificity of the Drosophila initiator caspase DRONC.
Cell death and differentiation·2008
The mechanism of peptide-binding specificity of IAP BIR domains.
Cell death and differentiation·2008
Overlapping cleavage motif selectivity of caspases: implications for analysis of apoptotic pathways.
Cell death and differentiation·2007
Metabolic stress-activated endothelial STING rewires the sinusoidal immune niche in MASLD.
The Journal of clinical investigation·2026
METTL1-mediated m7G modification of valine tRNAs drives metabolic adaptation in pancreatic ductal adenocarcinoma.
The Journal of clinical investigation·2026
Targeting the E3 ubiquitin ligase RNF10 ameliorates metabolic dysfunction-associated steatohepatitis in mice.
The Journal of clinical investigation·2026
Combined FAK and MEK inhibition suppresses chromosome 8 gain malignant peripheral nerve sheath tumors.
The Journal of clinical investigation·2026
Targeting KIT prevents brain arteriovenous malformations driven by ALK1-deficient angiogenic endothelial cells.
The Journal of clinical investigation·2026
Inhibiting menin attenuates high-fat diet-induced weight gain by limiting intestinal lipid absorption in mice.
The Journal of clinical investigation·2026
The Effect of Rivastigmine on Enhanced Glucose Metabolism and Enhanced Synaptic Plasticity in the Hippocampus of Aged Rats: A Sex-Dependent Study.
International journal of molecular sciences·2026
Statistical Models Validate Environmental Stability, Body Size and Life History Strategies as Predictors of Maximum Lifespan.
Animals : an open access journal from MDPI·2026
Estimating Survival, Growth, and Morphometric Relationships of Blue Crab (Callinectes sapidus) in North Carolina Using Mark-Recapture and Bayesian Approaches.
Animals : an open access journal from MDPI·2026
Environmental and Genetic Determinants of Early-Life Telomere Length in Tree Swallows.
Molecular ecology·2026
Enlarging viral mutation estimation: a view from the distribution of mutation rates.
Microbiology (Reading, England)·2026