Sudden hearing loss following drip intravenous pyelography with iohexol: a case report
Related Experiment Video
Updated: Oct 10, 2026

Intrathecal Application of a Fluorescent Dye for the Identification of Cerebrospinal Fluid Leaks in Cochlear Malformation
Published on: February 29, 2020
1Department of Otolaryngology, NTT-East Kanto Medical Center, 5-9-22 Higashi-Gotanda, Shinagawa-ku, 141-0022, Tokyo, Japan.
Abstract:
A 37-year-old male developed severe sensorineural hearing loss (SNHL) following drip intravenous pyelography with iohexol. We suggest that this hearing disturbance might have been caused by a delayed allergic reaction to iohexol or to its toxicity, because hearing loss developed several hours after the infusion of iohexol. No improvement in hearing was achieved after various treatments. This is the first report of SNHL possibly attributable to the adverse effects of iohexol.
Related Concept Videos
Imaging Studies V: Intravenous Urography and Retrograde Pyelography
Imaging Studies VII: Vascular Imaging
Acute Pyelonephritis II: Diagnostic Studies and Management
Acute Kidney Injury IV: Diagnostic Studies and Prevention
Imaging Studies III: Computed Tomography
Drug Accumulation During Multiple Dosing: Intermittent IV Infusions