Related Experiment Video
Updated: Oct 10, 2026

Automated 3D Optical Coherence Tomography to Elucidate Biofilm Morphogenesis Over Large Spatial Scales
Published on: August 21, 2019
A simple 2D biofilm model yields a variety of morphological features
1Department of Civil and Environmental Engineering, University of California, Berkeley, CA 94720-1710, USA. hermanowicz@ce.berkeley.edu
Abstract:
A two-dimensional biofilm model was developed based on the concept of cellular automata. Three simple, generic processes were included in the model: cell growth, internal and external mass transport and cell detachment (erosion). The model generated a diverse range of biofilm morphologies (from dense layers to open, mushroom-like forms) similar to those observed in real biofilm systems. Bulk nutrient concentration and external mass transfer resistance had a large influence on the biofilm structure.
Related Concept Videos
Biofilms
Microbial Morphologies
