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Assessment of neutrophil function in patients with septic shock: comparison of methods
C Wenisch1, P Fladerer, S Patruta
1Division of Infectious Diseases, Department of Internal Medicine I, University Hospital of Vienna, Vienna, Austria. christoph.wenisch@kfunigraz.ac.at
Clinical and Diagnostic Laboratory Immunology
|January 4, 2001
Abstract:
Patients with septic shock are shown to have decreased neutrophil phagocytic function by multiple assays, and their assessment by whole-blood assays (fluorescence-activated cell sorter analysis) correlates with assays requiring isolated neutrophils (microscopic and spectrophotometric assays). For patients with similar underlying conditions but without septic shock, this correlation does not occur.