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Updated: Aug 19, 2026

ADSC-sheet Transplantation to Prevent Stricture after Extended Esophageal Endoscopic Submucosal Dissection
Published on: February 10, 2017
[So-called spontaneous intramural dissection of the esophagus]
B Mathieu1, P Le Gall, A Mourani
1Service d'Hépato-Gastroentérologie, Hôpital Intercommunal de Fréjus-Saint-Raphaël, Fréjus.
Abstract:
We report two cases of spontaneous esophageal intramural dissection in two women aged 65 and 79 years. Initial symptoms were a constrictive retrosternal thoracic pain during a meal. Minor hematemesis accompanied by dysphagia or odynophagia appeared during the following hours. After excluding a cardiovascular emergency, diagnosis was confirmed by upper GI endoscopy that found a large mucosal longitudinal dissection; the lesion extended from mid-esophagus until short above the gastro-esophageal junction. Intramural parietal dissection characteristically appeared on barium swallow as a "double-barrelled" esophagus related to a thin radiolucent mucosal membrane separating the false and true lumens. Medical treatment with total parenteral nutrition, intravenous gastric antisecretory drugs, antibiotics in 1 patient was continued until symptoms disappeared; oral feeding was then started without incident. Follow-up endoscopic examinations confirmed complete healing. Regardless of etiology which remains speculative, spontaneous intramural dissection of the esophagus probably results from an intramural hematoma in most cases.
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