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Related Experiment Video

Updated: Jun 6, 2026

Dried Blood Spots - Preparing and Processing for Use in Immunoassays and in Molecular Techniques
11:28

Dried Blood Spots - Preparing and Processing for Use in Immunoassays and in Molecular Techniques

Published on: March 13, 2015

[HBsAg quantification: virological significance].

N Ben Slama1, S N Si Ahmed, F Zoulim

  • 1Hospices Civils de Lyon, Hôtel Dieu, Service d'hépatologie et de gastroentérologie, Lyon, France.

Gastroenterologie Clinique Et Biologique
|November 25, 2010
PubMed
Summary
This summary is machine-generated.

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Quantifying hepatitis B surface antigen (HBsAg) levels offers a new way to monitor hepatitis B virus infection. This marker can predict treatment success and HBsAg clearance, aiding in optimizing patient therapy.

Area of Science:

  • Hepatology
  • Virology
  • Immunology

Context:

  • Hepatitis B virus (HBV) infection is a global health concern.
  • Hepatitis B surface antigen (HBsAg) is a key serological marker for HBV infection.
  • Serum HBsAg levels correlate with intrahepatic covalently closed circular DNA (cccDNA), a measure of viral replication.

Purpose:

  • To explore the clinical utility of serum HBsAg quantification in managing hepatitis B.
  • To investigate HBsAg kinetics as a predictive marker for treatment outcomes.
  • To highlight the need for standardized assays and defined clinical cut-off values.

Summary:

  • Serum HBsAg quantification indirectly reflects the number of infected hepatocytes.
  • The decline kinetics of serum HBsAg may predict sustained virological response and HBsAg clearance.

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Last Updated: Jun 6, 2026

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Dried Blood Spots - Preparing and Processing for Use in Immunoassays and in Molecular Techniques

Published on: March 13, 2015

Real-Time Polymerase Chain Reaction-Based Detection and Quantification of Hepatitis B Virus DNA
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Real-Time Polymerase Chain Reaction-Based Detection and Quantification of Hepatitis B Virus DNA

Published on: December 15, 2023

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Modeling Hepatitis B Virus Infection in Non-Hepatic 293T-NE-3NRs Cells

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  • This approach could enhance monitoring and treatment optimization for hepatitis B.

    • Impact:

    • HBsAg quantification represents a promising tool for personalized hepatitis B treatment strategies.
    • Further prospective studies are needed to standardize assays and establish clinical predictive values.
    • This advancement could lead to improved patient management and outcomes in hepatitis B care.