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Updated: Jan 21, 2026

Multi-photon Imaging of Tumor Cell Invasion in an Orthotopic Mouse Model of Oral Squamous Cell Carcinoma
Published on: July 25, 2011
Management of an extended bone-invasive basal cell carcinoma of the median forehead
N Ben Slama1, J Adnot2, O Trost3
1Department of Oral and Maxillofacial Surgery, Rouen Normandy University, 1, rue de Germont, 76031 Rouen, France.
Abstract:
We report the case of a 35-year-old male patient managed for extended basal cell carcinoma of the median forehead, invading the frontal bone. Bone reconstruction was performed by a splitting of calvaria and skin reconstruction was performed using two frontal flaps dissected into complete vascular island, covering a skin defect of about 8cm in diameter (including safety margins). Wound healing was achieved after 4 weeks despite a median area of suffering and a temporary leak of cerebrospinal fluid of favorable evolution. The result at 5 years was excellent, with the patient's return to normal daily life and total satisfaction.
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