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Toward the functional analysis of the Dictyostelium discoideum genome
R Sucgang1, G Shaulsky, A Kuspa
1Department of Biochemistry, Baylor College of Medicine, Houston, Texas 77030, USA.
Abstract:
Dictyostelium discoideum is a useful model for molecular studies of cell biology and development. The 34-megabase Dictyostelium genome is currently being sequenced through the efforts of an international consortium. The genome is expected to encode 8-10,000 genes, including all those required for a free-living eukaryote capable of multicellular development. A complete description of the Dictyostelium genome will open the way toward the application of genome-based experimental approaches to studies of cell biology and development in this organism, and allow detailed physiological and evolutionary comparisons to other species.