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Updated: Aug 15, 2026

A Tandem Liquid Chromatography–Mass Spectrometry-based Approach for Metabolite Analysis of Staphylococcus aureus
Published on: March 28, 2017
Effects of microbial metabolites on catalase activity and growth of Staphylococcus aureus 6538 P
O V Bukharin1, S V Cherkasov, A V Sgibnev
1Institute of Cellular and Intracellular Symbiosis, Ural Division of the Russian Academy of Sciences, Orenburg.
Abstract:
The effects of cell extracts and supernatants of Lactobacillus spp. and Corynebacterium spp. on catalase activity and growth of Staphylococcus aureus 6538 P were studied. Intra- and extracellular metabolites of lactobacilli and corynebacteria inhibited catalase activity of S. aureus 6538 P. The growth of S. aureus 6538 P decreased after incubation with lactobacillus metabolites. The inhibitory effect of intra- and extracellular metabolites of lactobacilli and corynebacteria on catalase activity of S. aureus is a possible pathway of microbial interrelations responsible for the formation and/or development of microbial biocenoses.
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