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Microbial transformation of the eudesmane sesquiterpene plectranthone
1Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia. kyorabi@ksu.edu.sa
Journal of Natural Products
|January 5, 2001
Abstract:
Microbial transformation studies of plectranthone (1) have revealed that it was metabolized by a number of microorganisms. Using a standard two-stage fermentation technique, Beauvaria bassiana (ATCC 7159) produced five metabolites, 2-6. These metabolites were characterized on the basis of spectral data.