Related Experiment Videos
[Occurrence and susceptibility to antibiotics of Streptococcus pyogenes strains from purulent infections in soft
I Kania1, E Gospodarek, B Ulatowska
1Katedry i Zakładu Mikrobiologii AM w Bydgoszczy.
Abstract:
Occurrence and susceptibility to antimicrobial agents of Streptococcus pyogenes strains isolated from purulent infections of soft tissue were examined. The specimen was from hospital and ambulatory patients in 1996-1998. In general, 3665 samples were examined: 1841 wound swabs, 870 pus samples, 753 ulcer swabs and 101 from the decubitus ulcers. The ulcer of shank was the main diagnosis from which the Streptococcus pyogenes was isolated (38.8%). The susceptibility to antimicrobial agents according to the disc-diffusion method was analyzed among the 59 S. pyogenes strains. 10.2% strains with the MLSB resistance were detected. All S. pyogenes strains were susceptible to penicillin, new quinolons and glicopeptides.
Insights
Streptococcus pyogenes from soft tissue infections showed resistance to MLSB antibiotics. However, all strains remained susceptible to penicillin, new quinolones, and glycopeptides, indicating effective treatment options.
Area of Science:
- Microbiology
- Infectious Diseases
- Antimicrobial Resistance
Context:
- Focuses on Streptococcus pyogenes, a significant pathogen in soft tissue infections.
- Examines isolates from both hospital and ambulatory patients between 1996-1998.
- Analyzes a large sample size (3665) including wound swabs, pus, and ulcer swabs.
Purpose:
- To determine the occurrence and antimicrobial susceptibility of Streptococcus pyogenes in purulent soft tissue infections.
- To identify resistance patterns, specifically Macrolide-Lincosamide-Streptogramin B (MLSB) resistance.
- To evaluate the effectiveness of common antibiotics against these isolates.
Summary:
- 3665 samples yielded Streptococcus pyogenes, predominantly from shank ulcers (38.8%).
- Of 59 S. pyogenes strains analyzed, 10.2% exhibited MLSB resistance.
- All tested strains demonstrated susceptibility to penicillin, new quinolones, and glycopeptides.
Impact:
- Highlights the prevalence of S. pyogenes in soft tissue infections and identifies key sources.
- Provides crucial data on emerging antimicrobial resistance, particularly MLSB resistance.
- Confirms the continued efficacy of penicillin, new quinolones, and glycopeptides for treating these infections.