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St. Jude Medical prosthetic aortic valve malfunction due to pannus formation
Y Naito1, M Hachida, T Shimabukuro
1Department of Cardiovascular Surgery, Heart Institute of Japan, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan.
Abstract:
According to the literature, the incidence of pannus formation with the St. Jude Medical prosthetic aortic valve has been reported at 0.03% and 0.14% (per patient-year), with no case report of St. Jude Medical prosthetic aortic valve malfunction due to pannus formation. Between 1980 and 1999, 1,186 patients underwent aortic valve replacement at our institute. We encountered 2 aortic valve malfunctions due to pannus formation, including the case of a 53-year-old woman who suffered a St. Jude medical aortic valve malfunction 13 years after the initial operation. A second aortic valve replacement was successful and the postoperative course was uneventful. The possibility of pannus formation on St. Jude Medical aortic valves must thus be considered and its mechanism clarified.
Insights
Pannus formation can cause St. Jude Medical prosthetic aortic valve malfunction, a rare but serious complication. Further research is needed to understand and prevent this issue in patients with mechanical heart valves.
Area of Science:
- Cardiovascular Surgery
- Biomaterials Science
Background:
- Prosthetic aortic valve replacement is a common procedure.
- Pannus formation is a known complication of prosthetic heart valves, but its incidence and impact on St. Jude Medical valves require further investigation.
Observation:
- A review of 1,186 aortic valve replacements between 1980 and 1999 identified two cases of prosthetic valve malfunction due to pannus formation.
- One case involved a 53-year-old woman experiencing St. Jude Medical aortic valve malfunction 13 years post-implantation.
Findings:
- The incidence of St. Jude Medical prosthetic aortic valve malfunction due to pannus formation in this cohort was higher than previously reported in the literature.
- Pannus formation, a tissue overgrowth, can lead to mechanical heart valve dysfunction.
Implications:
- The findings suggest that pannus formation should be considered a potential cause of St. Jude Medical aortic valve malfunction.
- Further research into the mechanisms of pannus formation is crucial for developing preventative strategies and improving long-term outcomes for patients with prosthetic valves.