Related Experiment Video
Updated: Jul 23, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
Use of the Bayley Infant Neurodevelopmental Screener with low birth weight infants
C H Leonard1, R E Piecuch, B A Cooper
1University of California, San Francisco, CA 94143, USA. cleonard@peds.ucsf.edu
Insights
The Bayley Infant Neurodevelopmental Screener (BINS) effectively screens premature, low birth weight infants. It shows moderate predictive validity for identifying developmental delays when combined with other risk factors.
Area of Science:
- Neonatal development
- Pediatric screening tools
- Infant neurodevelopment
Background:
- Premature and low birth weight infants are at higher risk for developmental delays.
- Early identification of neurodevelopmental issues is crucial for timely intervention.
- Existing screening tools require validation for specific high-risk infant populations.
Purpose of the Study:
- To evaluate the Bayley Infant Neurodevelopmental Screener (BINS) as a screening tool.
- To assess the utility of BINS for premature infants with low birth weight (<1,500 grams).
Main Methods:
- 133 preterm infants (<1,500g) underwent BINS at 6.8 months (adjusted age).
- Infants later received Bayley Scales of Infant Development, Second Edition (BSID-II) at 12.9 months (adjusted age).
- BINS scores were correlated with BSID-II Mental Development Index (MDI) and Psychomotor Development Index (PDI) scores.
Main Results:
- BINS scores demonstrated significant associations with both MDI (r=.40) and PDI (r=.35) (p < .001).
- The BINS exhibited moderate predictive validity (67%-76%) in identifying infants with lower developmental functioning.
Conclusions:
- The BINS is a satisfactory screening instrument for low birth weight infants.
- Its effectiveness is enhanced when used alongside other established biologic and social risk factors.
Objective:
To examine the utility of the Bayley Infant Neurodevelopmental Screener (BINS) as a screening technique for premature, low birth weight infants.
Methods:
One hundred thirty-three preterm infants <1,500 grams received a BINS assessment at mean adjusted age 6.8 months and a Bayley Scales of Infant Development, Second Edition (BSID-II) assessment at mean adjusted age 12.9 months. Infants' BINS scores were compared to their BSID-II Mental Development Index (MDI) and Psychomotor Development Index (PDI) scores.
Results:
The BINS score showed significant association with the MDI (r =.40, p = <.001) and with the PDI (r =.35, p = <.001). The BINS showed moderate predictive validity (67%-76%) for identifying lower functioning infants.
Conclusions:
The BINS is a satisfactory screening tool for low birth weight infants when used in conjunction with other known biologic and social risk factors.

