Related Experiment Video
Updated: Aug 4, 2026
12:31
A Step by Step Protocol for Subretinal Surgery in Rabbits
Published on: September 13, 2016
Open retinotomy after submacular surgery
B A Cooper1, M A Thomas, N M Holekamp
1Department of Ophthalmology, Washington University, St. Louis, Missouri, USA.
American Journal of Ophthalmology
|December 22, 2000
Summary
Persistent open retinotomy after submacular surgery for presumed ocular histoplasmosis is common. Long-term follow-up shows no associated complications, suggesting this is a safe outcome in patients with ocular histoplasmosis.
Area of Science:
- Ophthalmology
- Retinal Surgery
- Histoplasmosis Research
Background:
- Submacular surgery is a treatment for choroidal neovascularization.
- Presumed ocular histoplasmosis can cause vision-threatening neovascularization.
- Surgical techniques aim to remove neovascular complexes while minimizing retinal damage.
Purpose of the Study:
- To document the occurrence of persistent open retinotomy after submacular surgery.
- To evaluate the long-term safety and implications of a persistent retinotomy in patients with presumed ocular histoplasmosis.
Main Methods:
- Retrospective review of 5 patients with presumed ocular histoplasmosis.
- Pars plana vitrectomy with surgical removal of submacular neovascularization.
- Utilized a small retinotomy technique, followed by a mean of 47 months postoperatively.
Main Results:
- A persistent open retinotomy was observed in all 5 treated eyes.
- No intraoperative or postoperative complications were attributed to the persistent retinotomy.
- Long-term follow-up (≥36 months) did not reveal adverse events related to the open retinotomy site.
Conclusions:
- Persistence of the retinotomy site is a potential outcome following submacular surgery.
- An open retinotomy site appears to be well-tolerated and safe in the long term for patients with presumed ocular histoplasmosis.
