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Published on: October 23, 2010
CD1d-restricted mouse V alpha 14 and human V alpha 24 T cells: lymphocytes of innate immunity
1Schultz Laboratory, Department of Molecular Biology, Princeton University, Princeton NJ 08544, USA.
Seminars in Immunology
|January 9, 2001
Abstract:
Mouse V alpha 14 T cells and their human homologs, V alpha 24 T cells, are prominent subsets of CD1d-restricted T cells. Here we discuss their striking similarities to B-1 B cells and gammadelta T cells and propose that these immune cells mediate various innate strategies in response to endogenous or exogenous danger signals.

