Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Dynamics of peroxisome assembly and function.

V I Titorenko1, R A Rachubinski

  • 1Dept of Cell Biology, University of Alberta, Edmonton, T6G 2H7, Alberta, Canada

Trends in Cell Biology
|January 9, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ring-substituted analogs of 3,3'-diindolylmethane (DIM) induce apoptosis and necrosis in androgen-dependent and -independent prostate cancer cells.

Investigational new drugs·2013
Same author

Yarrowia lipolytica cells mutant for the peroxisomal peroxin Pex19p contain structures resembling wild-type peroxisomes.

Molecular biology of the cell·2001
Same author

Peroxisome proliferator-activated receptor gamma ligands differentially modulate muscle cell differentiation and MyoD gene expression via peroxisome proliferator-activated receptor gamma -dependent and -independent pathways.

The Journal of biological chemistry·2001
Same author

The short heterodimer partner receptor differentially modulates peroxisome proliferator-activated receptor alpha-mediated transcription from the peroxisome proliferator-response elements of the genes encoding the peroxisomal beta-oxidation enzymes acyl-CoA oxidase and hydratase-dehydrogenase.

Molecular and cellular endocrinology·2001
Same author

Peroxisome biogenesis in the yeast Yarrowia lipolytica.

Cell biochemistry and biophysics·2001
Same author

The life cycle of the peroxisome.

Nature reviews. Molecular cell biology·2001

Peroxisomes assemble through dynamic subcompartment conversions and precursor fusion, revealing new roles in development. Further research is needed to understand this plasticity.

Area of Science:

  • Cell Biology
  • Biochemistry
  • Yeast Genetics

Background:

  • Peroxisomes are dynamic organelles with distinct subcompartments.
  • These subcompartments differ in protein import and undergo sequential conversions.
  • Peroxisomes have recently shown unexpected roles in developmental programs.

Purpose of the Study:

  • To highlight recent discoveries on peroxisome assembly and function.
  • To explore the dynamic nature of peroxisomes.
  • To suggest future research directions.

Main Methods:

  • Studies in human cells and the yeast Yarrowia lipolytica.
  • Analysis of peroxisomal subcompartment structure and protein import.
  • Investigation of peroxisome assembly pathways.

Related Experiment Videos

Main Results:

  • Peroxisomes comprise multiple distinct subcompartments.
  • Peroxisomal precursors fuse as an early step in assembly in Y. lipolytica.
  • Peroxisomes exhibit plasticity with roles in development.

Conclusions:

  • Peroxisome assembly is a multistep process involving precursor fusion.
  • Peroxisome function is highly dynamic and adaptable.
  • Further investigation is required to fully understand peroxisome plasticity and developmental roles.