Related Experiment Video
Updated: Oct 17, 2026

Simultaneous Affinity Enrichment of Two Post-Translational Modifications for Quantification and Site Localization
Published on: February 27, 2020
The expanding biology of post-translational modifications
1Department of Biophysics and Biochemistry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Abstract:
In this editorial, guest editor George Burslem and the Cell Chemical Biology editorial team introduce a special issue from Cell Chemical Biology on post-translational modifications! They present a collection of articles including several reviews, a primer, a spotlight, and various opinion pieces from a community of scientists studying the chemical biology of post-translational modifications.
Related Concept Videos
Covalently Linked Protein Regulators
These groups modify specific amino acids in a protein.
Covalently Linked Protein Regulators
These groups modify specific amino acids in a protein.
Regulation of Expression at Multiple Steps
Bacterial Protein Maturation
Protein Modifications in the RER
Broadly, these modifications can be categorized into four main categories — glycosylation, formation of disulfide bonds, assembly of protein subunits, and specific proteolytic cleavages like removal of signal sequences.
Protein Glycosylation
Glycosylation occurs in...
