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[Thyroid cancer in patients with hyperthyroidism]
J P Chigot1, F Ménégaux, K Keopadabsy
1Service de Chirurgie générale, digestive et endocrinienne, Hôpital de la Pitié, 83, boulevard de l'hôpital, F 75651 Paris. jean-paul.chigot@psl.ap-hop-paris.fr
Presse Medicale (Paris, France : 1983)
|January 10, 2001
Summary
The prevalence of thyroid carcinoma in hyperthyroidism is low, with similar rates to non-toxic goiter. Surgery for hyperthyroidism may favor total thyroidectomy due to these findings.
Area of Science:
- Endocrinology
- Surgical Oncology
- Pathology
Context:
- The relationship between hyperthyroidism and thyroid cancer prevalence is debated.
- Thyroidectomy is a common surgical intervention for hyperthyroidism.
Purpose:
- To determine the prevalence of thyroid carcinoma in patients undergoing surgery for hyperthyroidism.
- To compare these rates with those in non-toxic goiter.
Summary:
- A retrospective study of 861 patients with hyperthyroidism found thyroid carcinoma prevalence rates of 1.45% (solitary nodules), 4.1% (Graves' disease), and 4.9% (multinodular goiter).
- The majority (83%) of detected thyroid cancers were microcarcinomas.
- Surgical outcomes included 0.56% parathyroid morbidity and 1.6% recurrent hyperthyroidism.
Impact:
- Findings suggest hyperthyroidism may not directly cause thyroid cancer.
- Results support considering total or near-total thyroidectomy for hyperthyroid patients undergoing surgery.