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Mammary cancer in humans and mice: a tutorial for comparative pathology. The CD-ROM
R D Cardiff1, U Wagner, L Hennighausen
1Department of Pathology and Center for Comparative Medicine, University of California, Davis 95616, USA. rdcardiff@ucdavis.edu
Abstract:
This article introduces a CD-ROM containing whole-mount and histological images of normal growth and development of both the mouse mammary gland and the human breast. It also covers nonneoplastic lesions and neoplasias in both species including a catalog of lesions in genetically engineered mice. Instructions, with examples, on techniques such as whole-mount preparation, immunohistochemistry, in situ hybridization, and common histological stains are provided. The images are based on full-scale 1996 x 1640 pixel images at 300 pixels/ inch and are annotated. Every genetically engineered model has one or more accompanying citations. Tables are provided for orientation and organization. The CD includes zoom capabilities, a search engine, and a help mode.