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Risk factors of deep sternal wound infections in coronary artery bypass graft surgery

F D Wang1, C H Chang

  • 1Department of Medicine, Veterans General Hospital-Taipei and National Yang-Ming University, Taiwan, ROC.

The Journal of Cardiovascular Surgery
|January 10, 2001
PubMed

Insights

Deep sternal wound infections (DSWI) after coronary artery bypass graft (CABG) surgery are rare but serious. Re-operation for bleeding and longer operation times are key predictors of DSWI risk.

Area of Science:

  • Cardiovascular Surgery
  • Infectious Disease
  • Surgical Outcomes

Background:

  • Deep sternal wound infection (DSWI) following coronary artery bypass graft (CABG) surgery is infrequent but associated with significant morbidity and mortality.
  • Identifying risk factors is crucial for developing prophylactic strategies.
  • This study aimed to identify independent predictors of DSWI after CABG.

Purpose of the Study:

  • To identify significant risk factors for deep sternal wound infection (DSWI) after coronary artery bypass graft (CABG) surgery.
  • To inform prophylactic measures for high-risk patients.
  • To reduce the incidence of DSWI.

Main Methods:

  • A cohort of 620 patients undergoing CABG between 1996 and 1997 was analyzed.
  • Wound infections were classified using Centers for Disease Control (CDC) definitions.
  • Multivariate logistic regression identified independent predictors of DSWI.

Main Results:

  • The incidence of DSWI was 2.7% (17 patients).
  • Univariate analysis identified several potential risk factors, including re-operation for bleeding and operation time.
  • Multivariate analysis confirmed re-operation for bleeding and operation time as independent predictors of DSWI.
  • Staphylococcus, predominantly methicillin-resistant strains, was the most common pathogen.

Conclusions:

  • Re-operation for bleeding and prolonged operation time are independent predictors of deep sternal wound infection after CABG.
  • These findings can guide targeted preventative strategies for at-risk patients.
Abstract

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