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Biomarkers of oxidative stress: an analytical approach
P Thérond1, D Bonnefont-Rousselot, A Davit-Spraul
1Department of Biochemistry, Pharmacology and Toxicologie, Versailles Hospital, Le Chesnay, France.
Current Opinion in Clinical Nutrition and Metabolic Care
|January 11, 2001
Abstract:
Oxidative stress is implicated in many pathological processes and results from a disruption of the prooxidant/antioxidant balance. This review will focus on noninvasive biomarkers of radical-induced damage in biological fluids and particularly in blood. Special attention will be addressed to new analytical methods for the measurement of radical-mediated alterations in the integrity of lipids, proteins and DNA.