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[Latanoprost-associated recurrent herpes simplex keratitis].
Dios Castro E1, Maquet Dusart JA
1Servicio de Oftalmología, Hospital Universitario de Valladolid, Valladolid, España. enriquedios@hotmail.com
Archivos De La Sociedad Espanola De Oftalmologia
|January 11, 2001
Summary
Latanoprost treatment may trigger recurrent herpes simplex keratitis in patients with a prior history of ocular herpes infection. Discontinuation of latanoprost led to remission of herpetic keratitis episodes.
Area of Science:
- Ophthalmology
- Virology
Background:
- Herpes simplex keratitis (HSK) is a significant cause of corneal blindness.
- Recurrences of HSK can be triggered by various factors, including stress and immunosuppression.
Observation:
- A patient with a history of herpetic keratitis experienced recurrent epithelial HSK after initiating latanoprost therapy.
- The patient's ophthalmic history was notable for a single prior episode of herpetic keratitis 21 years before this presentation.
Findings:
- HSK episodes resolved only after latanoprost was discontinued.
- No further HSK recurrences were observed following latanoprost cessation.
Implications:
- Latanoprost use may be associated with recurrent HSK in susceptible individuals.
- Clinicians should consider potential links between latanoprost and HSK recurrence in patients with a history of ocular herpes simplex virus infection.