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CD1 and lipid antigens: intracellular pathways for antigen presentation

J Jayawardena-Wolf1, A Bendelac

  • 1Department of Molecular Biology, Schultz Laboratory, Room 416, Princeton University, Washington Road, Princeton, NJ 08544, USA.

Current Opinion in Immunology
|January 13, 2001
PubMed
Summary

The CD1 family of MHC-like molecules presents lipid antigens to T cells by sampling various cellular compartments. These molecules may have evolved to detect membrane lipid integrity or present microbial lipids to diverse T cell types.

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