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[Multi-channel data collection and visualization system for intramyocardial electrograms].

P Kastner1, W Wimmer, H Hutten

  • 1Cortronik Mess- und Therapiegeräte GmbH, Plüddemanngasse 67a, 8010 Graz, Austria.

Biomedizinische Technik. Biomedical Engineering
|January 13, 2001
PubMed
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This project developed a multichannel system for recording intramyocardial electrograms (IEGM) from paced and beating hearts. The system aids in visualizing excitation spread and measuring cardiac electrophysiology in animal models.

Area of Science:

  • Biomedical Engineering
  • Cardiovascular Physiology
  • Electrophysiology

Context:

  • Accurate recording of intramyocardial electrograms (IEGM) is crucial for understanding cardiac electrophysiology.
  • Existing systems may lack integrated pacing capabilities or user-friendly visualization tools.
  • Animal models are essential for studying cardiac excitation spread and drug effects.

Purpose:

  • To develop a multichannel data acquisition system for recording and visualizing intramyocardial electrograms (IEGM).
  • To integrate a programmable dual-chamber pacemaker for controlled cardiac stimulation.
  • To create a LabView-based graphical user interface for system control and data analysis.

Summary:

  • The developed system features multi-step signal processing including amplification, filtering (0.05-800 Hz), and AD conversion (12 Bit, 6.25 kHz).

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  • IEGMs can be recorded in unipolar or bipolar modes, with integrated pacing capabilities.
  • A microcontroller-driven LabView interface facilitates parameter programming, data acquisition, and real-time visualization.
  • Impact:

    • Enables precise monitoring of cardiac excitation spread and propagation velocity in animal experiments.
    • Facilitates the measurement of drug impacts and pathological changes on IEGM morphology.
    • Provides a versatile tool for cardiovascular research and preclinical studies.