Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Quality Control

Quality Control

Quality control is one of the three cyclical quality assurance activities that help keep a system under statistical control. Typical quality control activities include creating quality control charts, conducting proficiency testing, and documenting and archiving results.
Quality control helps track data, visualize trends, and identify variations, making it easier to detect deviations that may affect the accuracy of an analysis. One way to do this is by generating a quality control chart, which...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Deformation and Collectivity in Doubly Magic ^{208}Pb.

Physical review letters·2025

Same author

^{138}Ba(d,α) Study of States in ^{136}Cs: Implications for New Physics Searches with Xenon Detectors.

Physical review letters·2023

Same author

First Evidence of Axial Shape Asymmetry and Configuration Coexistence in ^{74}Zn: Suggestion for a Northern Extension of the N=40 Island of Inversion.

Physical review letters·2023

Same author

Comment on "g Factor of the ^{99}Zr(7/2^{+}) Isomer: Monopole Evolution in the Shape-Coexisting Region".

Physical review letters·2021

Same author

Publisher Correction: The observation of vibrating pear-shapes in radon nuclei.

Nature communications·2020

Same author

Addendum: The observation of vibrating pear-shapes in radon nuclei.

Nature communications·2020

Search research articles

Related Experiment Video

Updated: Jun 30, 2026

qPCR Is a Sensitive and Rapid Method for Detection of Cytomegaloviral DNA in Formalin-fixed, Paraffin-embedded Biopsy Tissue

qPCR Is a Sensitive and Rapid Method for Detection of Cytomegaloviral DNA in Formalin-fixed, Paraffin-embedded Biopsy Tissue

Published on: July 10, 2014

Quality control for nucleic acid tests: common ground and special issues.

¹BBI Clinical Laboratories, New Britain, CT 06053, USA. pgarrett@bbii.com

Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology

|February 13, 2001

Summary

This study examines quality control for nucleic acid testing, highlighting the need for better error detection and fewer false rejections in clinical laboratories. It proposes improvements for more reliable molecular diagnostic tests.

More Related Videos

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors

Published on: September 20, 2016

Assessment of DNA Contamination in RNA Samples Based on Ribosomal DNA

Assessment of DNA Contamination in RNA Samples Based on Ribosomal DNA

Published on: January 22, 2018

Related Experiment Videos

Last Updated: Jun 30, 2026

qPCR Is a Sensitive and Rapid Method for Detection of Cytomegaloviral DNA in Formalin-fixed, Paraffin-embedded Biopsy Tissue

qPCR Is a Sensitive and Rapid Method for Detection of Cytomegaloviral DNA in Formalin-fixed, Paraffin-embedded Biopsy Tissue

Published on: July 10, 2014

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors

Published on: September 20, 2016

Assessment of DNA Contamination in RNA Samples Based on Ribosomal DNA

Assessment of DNA Contamination in RNA Samples Based on Ribosomal DNA

Published on: January 22, 2018

Area of Science:

Clinical Laboratory Science
Molecular Diagnostics
Quality Management

Background:

Traditional quality control (QC) methods are applied to novel nucleic acid detection technologies.
There is limited understanding of error detection rates and false rejection probabilities for these QC practices.
This necessitates a review of current QC approaches in molecular diagnostics.

Purpose of the Study:

To review traditional QC practices in the context of nucleic acid testing.
To explore rationalized QC strategies for molecular assays.
To suggest actionable steps for enhancing the quality of nucleic acid tests.

Main Methods:

Literature review of traditional QC methodologies.
Analysis of QC applicability to nucleic acid amplification and detection techniques.
Discussion of statistical and risk-based approaches to QC.

Main Results:

Traditional QC may not be optimal for nucleic acid tests, potentially leading to undetected errors or unnecessary rejections.
A more tailored and rational QC approach is feasible and necessary.
Specific strategies can improve the reliability and efficiency of QC for molecular diagnostics.

Conclusions:

Current QC practices require adaptation for nucleic acid testing to ensure clinical validity.
Implementing a rationalized QC framework can improve diagnostic accuracy and laboratory efficiency.
Further research and development of QC protocols are essential for advancing molecular diagnostics.