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Laryngotracheoplasty for subglottic stenosis in Down Syndrome children: the Cincinnati experience

M E Boseley1, D T Link, S R Shott

  • 1Department of Pediatric Otolaryngology, Children's Hospital Medical Center, Burnet Ave., Cincinnati, OH 45229, USA.

International Journal of Pediatric Otorhinolaryngology
|February 13, 2001
PubMed

Insights

Children with Down Syndrome have a higher prevalence of subglottic stenosis (SGS). This study found an increased incidence of posterior glottic stenosis (PGS) in this population, though surgical outcomes are improving.

Area of Science:

  • Pediatric Otolaryngology
  • Genetics and Rare Diseases

Background:

  • Subglottic stenosis (SGS) surgical repair presents challenges in children with Down Syndrome.
  • Down Syndrome is associated with a higher prevalence of SGS compared to the general pediatric population.

Purpose of the Study:

  • To update surgical outcomes for laryngotracheoplasty in children with Down Syndrome over 15 years.
  • To compare these outcomes with the overall patient series.
  • To report the incidence of posterior glottic stenosis (PGS) in this specific group.

Main Methods:

  • Retrospective review of medical records for children with SGS and Down Syndrome (1982-1997).
  • Data collected included prior intubation, tracheotomy, GERD, SGS grade, and decannulation status.

Main Results:

  • Risk factors for SGS in Down Syndrome patients are similar to the general population.
  • SGS remains more prevalent in children with Down Syndrome.
  • A higher rate of posterior glottic stenosis (PGS) was observed in Down Syndrome patients compared to the overall series.
  • Decannulation rates in Down Syndrome children are approaching those of the overall series.

Conclusions:

  • SGS is a significant concern in children with Down Syndrome.
  • The increased incidence of PGS requires specific attention in surgical planning.
  • Surgical management for SGS in this population shows improving results, nearing those of the general pediatric population.

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